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KMID : 0357920020360010066
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Korean Journal of Pathology
2002 Volume.36 No. 1 p.66 ~ p.69
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Chordoid Glioma: A Case Report
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Kim Jang-Hee
Han Jae-Ho
Shim Chull
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Abstract
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The chordoid glioma is a recently recognized rare neoplasm of the third ventricle and hypothalamus and, as the name implies, has a chordoid appearance. Using histological, immunohistochemical and ultrastructural studies, we report a case of a 32-year-old man with a chordoid glioma in the third ventricle. Magnetic resonance T1-weighted images of the brain with homogenous contrast enhancement revealed a well circumscribed, isointense mass occupying the third ventricle. Histologically, the tumor showed cords and clusters of epithelioid cells within a mucinous background along with lymphoplasmacytic infiltrate, and appeared to be reminiscent of a chordoma or chordoid meningioma. Immunohistochemically the tumor cells were immunoreactlve for glial fibrillary acidic protein, vimentin and CD34 but negative for epithelial membrane antigen. Uitrastructural study revealed round to spindle shaped cells with abundant cytoplasmic intermediate filaments and cytoplasmic zonation.
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KEYWORD
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Brain Neoplasms, Glioma, Third Ventricle
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